The Modern Synthesis (MS) gene-centered population model of evolution is currently being challenged by the Extended Evolutionary Synthesis (ESS) organism-centered developmental model of evolution. The predictions of the EES are here examined with respect to the arguments of Edward Drinker Cope (1840–1897) for an organism-centered evolutionary process in which organisms both shape and are shaped by their environments such that the activities of the organisms themselves play a role in their own evolution.

In 1878 evolutionary theoretician Edward D. Cope published an eight-page paper filled with prescient ideas that clearly anticipated theoretical evolutionary topics that are actively being debated some 145 years later. An examination of these ideas and their modern counterparts is the primary objective of this essay. A proposal is also made to provide an answer to Cope’s Puzzle concerning the sequences of events involved in the evolution of adaptive animal structures. This article revisits Cope’s “The Relation of Animal Motion to (...) Animal Evolution” (published in _The American Naturalist_, volume 12, number 1, January 1878, pp. 40–48) for _Biological Theory_’s “Classics in Biological Theory” collection; Cope’s original paper is available as supplementary material in the online version of this article. (shrink)